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A01 Research Groups

Research and Development of Software Platform for Integrative Multi-Level Systems Biology


Yoshihisa Kurachi

(Professor, Graduate School of Medicine, Osaka University)

Research and development of a software platform for integrative multi-level systems biology

Laboratory HP



Hiroaki Kitano

(Principal Investigator, Open Biology Unit, Okinawa Institute of Science and Technology)

Continued development of a comprehensive computational platform for systems biology

Laboratory HP


Akira Amano

(Professor, the College of Life Sciences, Ritsumeikan University)

Parallel simulation platform for tissue organ model represented by model description language

Laboratory HP


Kengo Kinoshita

(Professor, Graduate School of Information Science, Tohoku University)

Development of new simulation methods at the molecular layer

Laboratory HP


Yoshiyuki Hari

(Associate Professor, Graduate School of Pharmaceutical Sciences, Osaka University)

Development of synthetic methodology to supply materials for understanding of physiological system

Laboratory HP



A02 Research Groups

Multi-Level Systems Biology of Cardiac Electrophysiological Activity


Naomasa Makita

(Professor, Graduate School of Biomedical Sciences, Nagasaki University)

Molecular Basis of Genetic and Functional Defects of Cardiac Ion Channels

Laboratory HP



Ryuji Inoue

(Professor, Faculty of Medicine, Fukuoka University)

Multi-level integrative analysis of arrhythmogenesis in stressed/remodeled heart

Laboratory HP



Yoshihiro Ishikawa

(Professor, Graduate School of Medical Science, Yokohama City University)

Integratation of neuronal and signaling regulation of cardiac myocytes

Laboratory HP


Haruo Honjo

(Associate Professor, Institute of Environmental Medicine, Nagoya University)

Dynamics of cardiac excitation and life-threatening arrhythmias

Laboratory HP


Kazuo Nakazawa

(Laboratory Chief, Research Institute, National Cerebral and Cardiovascular Center)

Integrative simulation of electrophysiological activities in the heart reflecting multi-level data

Laboratory HP



A03 Research Groups

Multi-Level Systems Biology of Small Molecular Dynamics in Circulation


Fumiyoshi Yamashita

(Associate Professor, Graduate School of Pharmaceutical Sciences, Kyoto University)

Integrative analysis of multiple molecular interactions in biological systems

Laboratory HP



Hiroyuki Kagechika

(Professor, Graduate School of Biomedical Science, Tokyo Medical and Dental University)

Development of Novel Chemical Modulators of Pleiotropic Actions of Nuclear Receptors

Laboratory HP


Hiroyuki Kusuhara

(Associate Professor, Graduate School of Pharmaceutical Sciences, The University of Tokyo)

Comprehensive analysis of factors regulating small compounds movement on tissue and organ levels

Laboratory HP


Hiroshi Suzuki

(Professor, The University of Tokyo Hospital, Faculty of Medicine, The University of Tokyo)

Analysis of disposition of small molecules determined by the functional cooperation of multiple organs

Laboratory HP



Project Management Committee


Members in Public Offering Groups




Ministry of Education, Culture, Sports, Science and Technology: Grant-in-Aid for Scientific Research on Innovative Areas
Establishment of Integrative Multi-level Systems Biology and its Applications